magical properties of sage

Magickal properties of Sage | Magickal herbs, Magical herbs, MagickNutrition12 Benefits and Uses of SageSage is a grass grappled in several kitchens around the world. Their other names include common sage, garden sage and Salvia officinalis. It belongs to the mint family, along with other herbs such as oregano, rosemary, basil and thyme (). Sage has a strong aroma and earthly flavor, so it is typically used in small quantities. Still, it is full of a variety of nutrients and important compounds. The sage is also used as a natural cleansing agent, pesticide and ritual object in the spiritual burning of the sage or burning. This green grass is available fresh, dry or in the form of oil, and has numerous health benefits. Here are 12 surprising health benefits of the sage. 1. High in several Sage Nutrients packs a healthy dose of vitamins and minerals. A teaspoon (0.7 grams) of earthly sage contains (): As you can see, a small amount of sage packs 10% of your daily needs (). The Sage also contains small amounts of magnesium, zinc, copper and vitamins A, C and E. In addition, this aromatic spice houses caffeic acid, chlorogenic acid, rhosmarinic acid, elagic acid and rutin, all of which play a role in their health-benefit effects (). Given that it is consumed in small quantities, the sage provides only tiny amounts of carbohydrates, calories, proteins and fiber. Abstract Sage is rich in nutrients, especially vitamin K, despite being low in calories. A teaspoon (0.7 grams) has 10% of its daily needs of vitamin K. 2. Charged with antioxidants Antioxidants are molecules that help fortify the defenses of your body, neutralizing potentially harmful free radicals that are linked to chronic diseases (). Sage contains more than 160 different polyphenols, which are chemical compounds based on plants that act as in your body (). Chlorogenic acid, caffeic acid, rhosmarinic acid, elagic acid and rutin, all found in the sage, are linked to impressive health benefits, such as a lower risk of cancer and a better brain function and memory (, ). One study found that drinking 1 cup (240 ml) of sage twice a day significantly increased antioxidant defenses. He also lowered total cholesterol and "bad" LDL cholesterol, as well as high "good" HDL cholesterol. Summary Sage is loaded with antioxidants that are linked to various health benefits, including better brain function and a lower risk of cancer. 3. May Support Oral HealthSage has antimicrobial effects, which can neutralize microbes that promote dental plaque. In a study, a mouthwash based on the sage was shown to effectively kill the bacterium Streptococcus mutans, which is notorious to cause dental cavities (, ). In a test-tube study, it was shown that a wise-based kills and stops the spread of Candida albicans, a fungus that can also cause cavities (, ). One review noted that the sage can treat throat infections, dental abscesses, infected gums and mouth sores. However, more human research is needed to make general recommendations (). Abstract Sage has antimicrobial properties that can kill microbes that encourage the growth of the dental plate. 4. May Ease Menopause SymptomsDuring menopause, your body experiences a natural decline in estrogen. This can cause a wide range of nasty symptoms. Symptoms include hot flashes, excessive sweating, vaginal dryness and irritability. The common sage is traditionally used (a). It is believed that compounds in the sage have properties similar to estrogen, allowing them to bind certain receptors in their brain to help improve memory and treat hot flashes and excessive sweat (). In one study, the daily use of a sage supplement significantly reduced the number and intensity of hot flashes for eight weeks (). Summary Sage can help reduce the intensity and frequency of menopause symptoms, such as hot flashes and irritability. 5. It can reduce blood sugar levels Common sage leaves have traditionally been used as a remedy against diabetes. Human and animal research indicates that it can help reduce blood sugar levels. In a study, the sage extract reduced blood glucose levels in rats with type 1 diabetes by activating a specific receptor. When this receptor is activated, it can help clear the excess of free fatty acids in the blood, which in turn improves (, ). Another study in mice with type 2 diabetes found that sage tea acts as metformin, a medication prescribed to administer blood sugar in people with the same disease (). In humans, it has been shown that the sage leaf extract and improves insulin sensitivity with a similar effect such as rosiglitazone, another antidiabetes medication (). However, there is still not enough evidence to recommend the wise as treatment of diabetes. More human research is needed. Summary While the sage can reduce blood sugar levels by increasing insulin sensitivity, more human research is needed. 6. May Support Memory and Brain Health Sage can help support your brain and memory in several ways. For one, it is loaded with compounds that can act as antioxidants, which have been shown to cushion the defense system of your brain (, ). It also seems to stop the breakdown of the acetylcholine of the chemical messenger (ACH), which has a role in memory. ACH levels seem to fall into Alzheimer's disease (, ). In one study, 39 participants with mild to moderate Alzheimer's disease consumed either 60 drops (2 ml) of a sage extract supplement or a placebo daily for four months. Those who took the sage extract were best performed in tests that measured memory, problem solving, reasoning and other cognitive skills (). In healthy adults, the sage was shown in low doses. Higher doses also increase mood and increase alert, calm and content (). In young and older adults, the wise seems to improve memory and (, ). Abstract Studies show that the sage can improve memory, brain function and symptoms of Alzheimer's disease. 7. May Lower 'Bad' LDL Cholesterol Every minute, more than one person in the United States dies from heart disease (). High "bad" LDL cholesterol is a key risk factor for heart disease, affecting one in three Americans (). The sage can help lower the "bad" LDL, which can accumulate in the arteries and potentially cause damage. In one study, the consumption of sage tea twice a day lowered LDL cholesterol and total blood cholesterol while the increase of "good" HDL cholesterol after only two weeks (). Several other human studies illustrate a similar effect with sage extract (, , ). Abstract Sage intake and sage products have been shown to reduce the "bad" LDL cholesterol levels and raise the "good" HDL cholesterol levels. 8. It can be protected against certain cancers Cancer is a major cause of death in which cells grow abnormally. Curiously, animal and test-tube studies show that the sage can fight certain types of cancer, including those of the mouth, colon, liver, cervix, breast, skin, and kidney (, , , , , , , , , , , , , ).In these studies, sage extracts not only suppress the growth of cancer cells, but also stimulate cell death. While this research is encouraging, human studies are needed to determine whether the wise is effective in human beings. Abstract Test-tube and animal research suggest that the sage can fight certain cancer cells, although human research is needed. 9–11. Other Potential Health Benefits The wise and their compounds are linked to several other health benefits. However, these benefits have not been extensively investigated. Abstract Sage has been related to other potential health benefits, such as diarrhea relief, support bone health and combat skin aging. 12. Easy to add to your DietSage comes in various ways and can be used in various ways. Fresh sage leaves have a strong aromatic flavor and are the best used in dishes. Here are a few ways to add fresh sage to your diet: Dry sage is often preferred by cooks and comes land, rubbed or whole leaves. Here are a few ways to use the dry sage: You can also buy sage products, such as sage tea and sage extract supplements. Summary Sage is incredibly versatile and easy to add to soups, stews and baked dishes. It is available fresh, dry or ground. Do you have side effects? The wise is considered safe without reported side effects (). However, some people are concerned about thujone, a compound found in the common sage. Animal research has found that high doses of thujone can be toxic to the brain (). That said, there is no good evidence that thujone is for humans (). In addition, it is almost impossible to consume toxic amounts of thujone through food. However, drinking too much sage tea or ingesting essential sage oils, which should be avoided in any case, may have toxic effects. To be on the safe side, limit the consumption of sage tea to 3-6 cups a day (). Otherwise, if you are worried about thujone in common wise, then you can simply consume the Spanish sage instead, as it does not contain thujone (). Abstract The sage is safe to eat and has no reported side effects, although consuming essential sage oils or too much sage tea may be linked to adverse effects. The Bottom LineSage is one with several promising health benefits. It is high in antioxidants and can help support oral health, help brain function and reduce blood and cholesterol sugar levels. This green spice is also easy to add to almost any dish of flavor. You can enjoy fresh, dry or tea. Read this now.

Warning: The NCBI website requires JavaScript to operate. Chemistry, Pharmacology and Medical Property of Sage (Salvia) to prevent and cure diseases such as obesity, diabetes, depression, dementia, lupus, autism, heart disease and cancerMohsen Hamidpour1Department of Hematology and Blood Banking, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Rafie Hamidpour2 Herbal Medicine Department, Pars Bioscience, Leawood, KS, USA. Soheila Hamidpour3 Herbal Medicine Department, Pars Bioscience, Leawood, KS, USA. Mina Shahlari4 Herbal Medicine Department, Pars Bioscience, Leawood, KS, USA. Abstract For a long time, sage species have been used in traditional medicine for pain relief, protecting the body against oxidative stress, free radical damage, angiogenesis, inflammation, bacterial infection and viruses, etc., Several studies suggest that sage species can be considered for drug development due to their pharmacology and therapeutic activities reported in many countries of Asia and the Middle East. These studies suggest that the species of Salvia, in addition to treating minor common diseases, could potentially provide novel natural treatments for the relief or healing of many serious and life-threatening diseases such as depression, dementia, obesity, diabetes, lupus, heart disease and cancer. This article presents a thorough analysis of the botanical, chemical and pharmacological aspects of the wise (Saliva). INTRODUCTION The Salvia genus, commonly known as wise, is the largest member of the Lamiacea or Menta family that contains more than 900 species worldwide.[,] The plants are mostly aromatic and perennial [Figure and ], with flowers in different colors [].[] Many species of Salvia, including Salvia officinalis (common section), are native to the Mediterranean region and some of the species of Salvia have been used worldwide as flavoring spices and traditional herbal medicines.[,]Salvia officinalisSage officinalis "senseflowers"Salvia of the salvia disease has traditionally been used for the treatment of digestive and circulatory alterations. In addition, it has been shown that essential oil of sage has carminative, antispasmodic, antiseptic and astringent properties.[,]The essential oil of the species of Sage has various compositions depending on the genetic, climatic, seasonal and environmental factors.[] Some chemical compounds such as flavonoids, terpenoids and essential oils are present in different species of Sage [].[] Essential oils are very important sources for the detection of anticancer, antimicrobial, antioxidants and free radical scam agents.[] S. officinalis (common sage) is considered to have the most essential oil compared to other species of Salvia.[ ,] Wise Sheet – Tricomas are visible In all of the sample analysed of S. officinalis, the main components, although present in different concentrations, are: 1.8-cineole, camphor, terminaleol, terminalyl acetate, camphene, α- and β-thujone, linalool, α- and β-caryophyllene, α-humulene, α- and β-pinoridyl, acid Studies have shown that some biological properties of the essential oil of Salvia depend on camphors, 1.8-cines, α-thujone and β-thujone.[] The essential oil of sage contains about 20% camping, and as the leaves expand, the content of camping also increases.[] In a study, it was reported that the most powerful scam compounds were α-thujone and β-thujone, natilla acetate, camphor, chin and 1.8-cinol in essential oil.[] In the same study, the essential oil of Melissa officinalis and S. officinalis showed better antioxidant activities than other Lamiaceae plants. []The sage is also a natural source of flavonoids and polyphenolic compounds [] (e.g. carnoid acid, rhosmarinic acid and caffeic acid) that have strong antioxidant, radical and antibacterial activities.[] Most phenolic acids in the Salvia species are derived from the caffeic acid that is the building block of a variety of metabolites of plants.[] Caffeic acid plays a central role in the biochemistry of Lamiaceae plants, and is mainly presented in the form of dimer as rosmarinic acid.[] Carnosic acid and rhosmarinic acid, which are present in high concentrations in the extract of sage plants, have shown strong antioxidant properties.[] Ursolic acid, also a component of sage, has strong anti-inflammatory properties, and in the preparations of the sage, is considered as a quality control measurement for the anti-inflammatory effects of different solutions. []Danshensu and Salvia miltiorrhiza monoterpenoids. All these compounds contain catechelo functionalities. officinalis has numerous common names. Some of the best-known names include sage, common sage, garden sage, golden sage, kitchen sage, true sage, culinary sage, dalmatian sage and broad sage. The cultivated forms include purple sage and red sage. In Turkey, S. officinalis is widely known as adaçayı, which means "tea de la island". In the Levant, it's called maramia. CHEMICAL COMPOSITION In the commonly known wise form of S. officinalis, a total of 28 components was identified []. The main components in the sage oil were 1.8-cinole, camphor, α-thujone, β-thujone, terminaleol and viridiflorol. Chemotypes of the wise were not determined in the samples investigated. The concentrations of the main compounds in the drugs obtained from different types of sage and in different places varied around the same range as the concentrations of these compounds in the drug oils obtained from other countries. The comparatively high concentration of toxic thujones appears to be characteristic of cultivated sage leaves in different places as well. Table 1Composition of essential oil (% of the main components) of the wise Salvia officinalis collected as a sample[] ANIOXIDANT ACTIVITY Antioxidants play a very important role in the protection of the body against oxidative stress and free radical induced damage that are the cause of various diseases such as diabetes, heart disease, cancer, brain dysfunction, weakened immune system, etc. In a study on the antioxidant activity of many plant extracts, such as the sage (S. officinalis), it was found that phenolic and flavonoid compounds are primarily responsible for the free antioxidant and radical effects of this plant.[,] Phenolic compounds such as carnosol, carnosic acids and rhosmarinics, rhosmadial, rosmanol, epirosmanol, methylcarnosate and luteoline-7-O-β-glucopyranoside have high antioxidative activity and are usually extracted from ethanol salvia.[] Phenolic compounds can stimulate endogenous antioxidant defense systems or reactive scavenge species. []The antioxidant properties of the sage have been studied intensely, and are related to the presence of rhosmarinic acid and carnosic acid.[,] In addition, the salvianoic acid, which is a rosmarinic acid dimer isolated from the sage extract, showed high antioxidant activity and is a very significant scammer of free radicals [].[] It has been shown that the aqueous extract of S. officinalis has antioxidant and antiviral effects. In a study, it was observed that after drinking sage tea (common sage) for 2 weeks, the antioxidant state of the liver improved. [] Salvianoic acids of Salvia mitiorrhiza. All of these compounds contain catecolMEMORY moietiesAmong many herbal extracts, the species of Salvia are known for the beneficial effects on the disorders of memory, depression and cerebral ischemia.[,] S. officinalis (common section), Salvia lavandulaefolia (Spanish section), and Salvia miltiorrhiza (Chinese section) have been used for centuries as restorers of lost or declining mental functions, as in Alzheimer's disease (AD).[,] In AD, the acetiling corelinesterase enzyme (AChE) is responsible for the transfer of degrading and inactive signals AChE inhibitor drugs act by counteracting acetylcholine deficit and improving acetylcholine in the brain.[] The essential oil of S. officinalis has shown that it inhibits 46% of AChE activity to a concentration of 0.5 mg/ml.[] A study shows that S. officinalis improves memory and cognition, and with a growing dose, the mood rises as well as alertness, calm and increased contension.[] A randomized double-blind clinical trial has shown that an ethanol extract from the common sage (S. officinalis) as well as the Spanish sage (S. lavandulaefolia) is effective in managing mild to moderate DAD, and the study on patients showed no adverse effect on them in the taking of sage.[,] Management of S. lavandulaefolia (Spanish state) has improved speed. It has also been reported that the essential oil of Salvia will improve the immediate remembrance of words. [] Several studies have investigated the effects of the aromas of essential plant oils on cognition and mood.[] The aroma of S. officinalis produced a significant improvement effect on the quality of the memory factor derived from the Cognitive Drug Research (CDR) system. The findings suggest that the aromas of essential oils of the Salvia species have some, but not all the effects found after oral consumption of the herb.[] Antioxidant and anti-inflammatory properties of S. officinalis or S. lavandulaefolia can offer long-term protection in dementia pathogenesis.[] In addition, properties that increase the mood of grass may have applications in the treatment of advanced dementia, in which disturbed mood and characteristic agitation as an important problem.[] There is no report of negative side effects associated with S. officinalis or S. lavandulaefolia despite many years of use. [] The cytoprotective effect of the sage against Aβ toxicity (amyloid beta plates) in neuronal cells has also been tested by the data presented in a study that provides the pharmacological basis for the traditional use of the sage in the treatment of AD.[] Romarinic acid as a component of the sage has shown neuroprotective, antioxidative and antiapoptotic effects against Aβ toxicity, and this could contribute, at least in part, to the neuroprotective effect of the sage. Therefore, it is possible that rosmarinic acid, the very low toxic natural compound, may be used as a therapeutic agent in the treatment of AD. []DIABETESS. officinalis has been used as a traditional remedy against diabetes in many countries and its effects of glucose-low have been shown in animal studies.[] In a study, it was found that the methanolic extracts of S. officinalis significantly decreased serum glucose in type I diabetic rats without affecting pancreatic insulin production.[] An aqueous extract of S. officinalis has been found to exhibit activities similar to insulin. [] In one study, the consumption of sage tea (common sage) (300 ml, twice a day) showed an increase in antioxidant defenses and improved the lipid profile, without causing hepatotoxicity or inducing any adverse effect, such as changes in blood pressure, heart rate and body weight, which can indirectly improve the diabetic condition.[] S. officinalis tea infusions have proven to be as effective as metformin, which is an oral antidiabetic medication used for the treatment of type II diabetes, and act by reducing the production of hepatic glucose, as well as increasing the action of insulin.[] In many studies, it was found that the sage extract had a hypoglycemic effect on diabetic animals and that in the future additional research should take into account the additional therapeutic effects of this plant. [] CANCERCancer is characterized by abnormal growth in cells that tend to proliferate uncontrolled, and in some cases spread to other parts of the body.[] The important factor in the proliferation and spread of cancer cells is the ability of tumors to produce a large number of new blood vessels, known as angiogenesis.[] Most primary solid tumors depend on angiogenesis for survival, growth, invasion and metastasis.[] It was found in a study that the extract of S. officinalis in pharmacological concentrations inhibits in vivo angiogenesis, which could be a new starting point for the development of a new anti-angigen medication.[] Ursolic acid found in the sage effectively inhibits angiogenesis, the invasion of tumor cells and metastasis, and suppresses lung colonization of in vivo B16 melanoma cells.[] Colorectal cancer (CRC) is a common type of cancer and a significant cause of mortality in Western societies. It is developed by genetic and epigenetic alterations that transfer normal colon cells to proliferating cells.[] This study has shown that dietary compounds can change the epigenetic state. Many food plants are rich in bioactive compounds and have proven to possess anticancer properties.[] The effect of herbal tea was studied in the prevention of colon cancer in rats. It was found that the S. officinalis water extract significantly decreased the in vitro DNA damage induced by H2O2. []Some diterpenoids isolated from the roots of S. officinalis have been found to have cytotoxic and DNA activity in human colon carcinoma Colon Colon Colon Colon Colon Colon Colon Colon Colon Colon Colon Colon Colon Colon Colon Colon Colon Caco-2 and Human HepG2 cells in vitro conditions.[] The sesquiterpene fraction of S. officinalis containing α-humulene showed a strong cytotoxic activity in the LNCaP human prostate carcinoma cells.[] In addition, trans-caryophyllene, which is the main component of the sesquiterpene fraction in S. officinalis, shows high cytotoxic activity against melanotic melanoma and renal adenocarcinoma cells.[] The presence of α-humulene as a component of S. officinalis demonstrated a strong cytotoxic activity in the cells of human prostate carcinoma LNCaP.[]Libyan salvia (Lebanon sage) is one of the species of salvia used in traditional medicine, which has been used for many years to cure diseases such as abdominal pains, headaches, indigestion, and strong heart disorders.[] The components of the essential oil of the Lebanese sage were identified by gas chromatography, and three of the components containing on average 9.1 per cent of the camphors (Ca), 1.3 per cent α-terpineol (Te), and 1.1 per cent of the lymphalile acetate (Ly) were held responsible for the antibacterial, antifungal, anti-inflammatory and antitumor effects of oil.[] In this study, Ly, Te and Ca synergically induced the arrest of the cell cycle and apoptosis resulting in the inhibition of the growth of the cancer cell lines of the human colon, HCT-116 (p53+/+ and p53−/−), without any effect on the growth of normal lines of human intestinal cells. [ CHOLESTEROL] The metabolite profile of S. miltiorrhiza (SM) or the Chinese sage is similar to that of the common sage, and recently, it was shown that a SM extract was able to lower the plasma cholesterol, low-density lipoprotein (LDL) and triglycerides (TGs), as well as increase the levels of high-density lipoprotein (HDL) in lipidic rats. [] The extract of S. officinalis is found to activate the receptor gamma activated by peroxidized proliferator (PPARγ) which is a regulator of genes involved in energy spending, as well as the metabolism of lipids and glucose, and its activation improves the HDL/LDL ratio and reduces TG in serum, reduces insulin resistance, and reduces the size of the adipose tissue.[fat] It has been shown that extracts from some species of schist are effective in the prevention of cardiovascular diseases due, at least in part, to the prevention of oxidation of LDL-cholesterol. []OBESITYWeight and obesity are recognized to cause a number of abnormalities, such as type II diabetes, dyslipidemia, hypertension, etc., which are all major risk factors in the development of serious diseases such as cardiovascular diseases, chronic kidney diseases and many others.[] To regulate fat absorption, the effective way is to reduce body weight and obesity. [] Pancreatic lipasa is well known for playing an important role in lipid digestion.[] In several studies on anti-obese components of natural medicine, the effects of S. officinalis and its active components were investigated in pancreatic lipase activity and lipid digestion.[] The methanolic extract (MeOH) of the leaves of S. officinalis L. significantly inhibited the activity of pancreatic lipasa and suppressed the elevation of the TG serum in mice loaded with olive oil.[] Carnosic acid and carnosol are two of the isolated diterpenes of the methanolic extract of S. officinalis with an inhibitive activity in pancreatic lipasa. Carnosic acid also significantly inhibited the elevation of TG in mice loaded with olive oil and reduced body weight gain and the accumulation of epidididididimal fat in mice fed with a high diet after 14 days.[] In the course of several studies on anti-obese components of natural medicine, the extract of S. officinalis leaves showed inhibiting effect against pancreatic lipasa activity and was finally effective in reducing body weight and obesity. [] HOT FLASHESMenopause is considered a physiological adjustment process to an altered hormonal balance.[] Menopausic symptoms include hot flashes, insomnia, night sweating, dizziness, headaches and palpitations. These symptoms reflect the body's adaptation to estrogen deprivation that affects several central neurotransmitters. []Sage (S. officinalis) has traditionally been used to treat sweat and menopausal hot flashes, as well as to relieve associated menopausal symptoms.[] The effectiveness of the sage for the treatment of hot flashes during menopause was tested by a multicentered open clinical trial.[] A preparation of fresh sage demonstrated the clinical value in the treatment of hot flashes and associated menopausal symptoms.[] Once a day the application of the fresh sage extract showed good clinical value in terms of safety, effectiveness and tolerance in the treatment of menopausic hot flashes and climatic symptoms, validated by statistical analysis and clinically relevant verdict of patients and doctors.[] The findings of the study provide a scientific rationality for the use of the sage in popular medicine, offering a valuable choice for patients and healthcare providers who seek alternative approaches for the treatment of menopausal hot flashes and climate complaints. [] ACTIVITY A study on the antibacterial effect of the sage against selected bacteria of in vitro dispossession indicates that the aqueous extract of the sage performed a significant antibacterial activity and was more effective against Bacillus mycoides, Bacillus subtilis, Enterobacter cloacae, and Proteus sp.[] This has made the essential oil of sage a good alternative to traditional antibiotics, as well as food preservatives. [] The findings of a study support the view that the hydroalcoholic extract of S. officinalis has an inhibiting effect of growth in some dental caries that cause bacteria such as the Streptococcus mutans, Lactobacillus rhamnosus and Actinomyces viscosus. Based on this study and the global interest in using traditional treatments rather than chemical solutions, S. officinalis with its bactericidal effect could be a natural remedy for the treatment of diseases that affect the mouth and teeth.[] One study showed that the sage, along with different plant extracts, was comparable to synthetic preservatives, and the result confirmed that the aqueous extract of S. officinalis can be used in biotechnology as a natural preservative ingredient in the food industry. [] A study of the antibacterial activities of the essential oil of S. officinalis showed that the most concentrated essential oil of sage exhibited a better efficiency than antibiotics. [] ACTIVITY OF ARREGLO Based on the medicinal use of the sage in diarrhea and abdominal spasm, the raw sage extract was tested for its antidiarrheal and anti-spasmodic activities using in vitro and in vivo trials. A study showed that the raw extract provides protection against diarrhea through its inhibiting effect on intestinal motility by the presence of some intestinal relaxient components.[] The data from a study suggest that the raw extract of S. officinalis has anti-diarrheal and anti-spasmodic activities, mediated possibly by activating voltage-sensitive K+ channels, along with a weak Ca+ antagonist effect.[] Therefore, this study provides pharmacological basis for the medicinal use of S. officinalis in hyperactive intestinal disorders such as abdominal colic and diarrhea. [] SAGE TOXICITYIn what we know, there are no reports of negative side effects associated with S. lavandulaefolia or S. officinalis despite their use for many centuries.[] The normal use of the sage is very safe; however, there could be an adverse effect on the use of S. officinalis in excessive amount, which can be caused by the high content of thujone.[] A study has shown that S. lavandulaefolia (Spanish essence), compared to S. officinalis (common section), has similar compositions without the content of thujone, which makes it more suitable for those interested in excessive use of the sage as treatment. [] CONCLUSION The aim of this work is to review recent progress in the exploration of scale (Sage Sword) as phytotherapy and to illustrate its potential as a therapeutic agent. Salvia species can represent a natural, safe and effective treatment for many diseases and their symptoms. In recent decades, with increased pharmacological knowledge of the beneficial effects of the sage, especially S. officinalis, these herbal drugs with antibacterial, antioxidant, anti-inflammatory, free radical scavenging and antitumor activities have been found to be very effective in the development of new natural drugs to prevent, control and treat many minor health problems, as well as more serious and complicated diseases such as diabetes, Alzheimer's and cancer. It should be noted that doctors should remain cautious until more defined studies demonstrate the safety, quality and effectiveness of S. officinalis. For these reasons, extensive pharmacological and chemical experiments, together with human metabolic studies, should be the center of our future studies, and the additional potential of S. officinalis should be used in new therapeutic drugs and provide a basis for future research on the application of medicinal plants. REFERENCESFormats: Share , 8600 Rockville Pike, Bethesda MD, 20894 USA

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